Abstract
Tardive dyskinesia (TD) is a type caused by the use of different medications. The pathogenesis of TD is associated with dopamine receptor blockade, gamma-aminobutyric acid depletion, cholinergic deficiency, oxidative stress, impaired synaptic plasticity, and neurotoxicity. TD most often occurs after taking metoclopramide, antipsychotics, antidepressants, calcium channel blockers, and other drugs. The review considers an adequate assessment of the potential risk of TD when the patient uses prescribed drugs, as well as the monitoring and correction of risk factors for TD, discontinuation or replacement of drugs that potentially cause TD, as well as its treatment.
Highlights
Дискинезия, вызванная приемом различных лекарственных средств (ЛС), расценивается как тардивная (ТД)
Tardive dyskinesia (TD) is a type caused by the use of different medications
The pathogenesis of TD is associated with dopamine receptor blockade, gamma-aminobutyric acid depletion, cholinergic deficiency, oxidative stress, impaired synaptic plasticity, and neurotoxicity
Summary
Остроумова Т.М.1, Толмачева В.А.1, Остроумова О.Д.2,3, Парфенов В.А.1 1Кафедра нервных болезней и нейрохирургии Института клинической медицины ФГАОУ ВО «Первый Московский государственный медицинский университет им. Сеченова (Сеченовский университет)» Минздрава России, Москва, Россия; 2ФГБОУ ДПО «Российская медицинская академия непрерывного медицинского образования» Минздрава России (РМАНПО Минздрава России), Москва, Россия; 3ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Drug-induced tardive dyskinesia Ostroumova T.M.1, Tolmacheva V.A.1, Ostroumova O.D.2,3, Parfenov V.A.1 1Department of Nervous System Diseases and Neurosurgery, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow, Russia; 2Russian Medical Academy of Continuing Medical Education, Ministry of Health of Russia, Moscow, Russia; 3N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, Moscow, Russia 111, Rossolimo St., Build. Tardive dyskinesia (TD) is a type caused by the use of different medications. The review considers an adequate assessment of the potential risk of TD when the patient uses prescribed drugs, as well as the monitoring and correction of risk factors for TD, discontinuation or replacement of drugs that potentially cause TD, as well as its treatment
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
