Abstract

The incidence of drug-induced myopathic disorders is unknown. Estimates depend in part on definitions used. Cholesterol-lowering agents have been singled out as common offenders. However, the large number of available drugs, polypharmacy especially among the elderly, and known risk factors make the incidence of mild muscle disorders likely more common than suspected, but severe myopathies are likely rare. This article considers factors contributing to drug-induced myopathies and reviews examples of offending drugs.

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