Abstract
© 2013 The Authors. doi: 10.2340/00015555-1363 Journal Compilation © 2013 Acta Dermato-Venereologica. ISSN 0001-5555 Drug-induced hypersensitivity syndrome (DIHS), also known as drug rash with eosinophilia and systemic symptoms (DRESS), is a severe, adverse drug reaction characterized by skin rash, fever, lymphadenopathy, hepatitis and haematological abnormalities (1, 2). The presence of human herpes virus (HHV)-6 reactivation is considered to be a diagnostic criterion for DIHS but not for DRESS. The most common causative drugs are carbamazepine, phenytoin, phenobarbital, mexiletine, dapsone, salazosulphapyridine, minocycline and allopurinol (3). We report here a case of DIHS/DRESS caused by clindamycin, which was confirmed using the lymphocyte transformation test (LTT) and patch testing.
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