Drug Effect of Loxofen Sodium Tablets on Pain Relief of Periodontal Endodontic Syndrome and its Influence on Inflammatory Factors

Abstract

To investigate the effect of loxofen sodium tablets on the pain relief of periodontal and pulp syndrome and its influence on the level of inflammatory factors and to investigate the medicinal value of loxofen sodium tablets and to provide reference for the treatment of periodontal and endodontic syndrome is the objective of the study. 102 patients with periodontal endodontic syndrome were randomly divided into treatment group (51 patients) and control group (51 patients). The treatment group was treated with loxofen sodium tablets, while the control group was treated with ibuprofen sustained-release capsules. After treatment, the clinical efficacy, pain score, inflammatory factors levels and adverse incidence of the two groups were recorded. The total effective rate of the treatment group was 78.43 % higher than 58.83 % of the control group (p<0.05). Before treatment, there were no significant differences in pain score and inflammatory factor levels between the two groups (p>0.05). After medication, the improvement of pain in treatment group was better than that in control group (p<0.05). After treatment, the level of inflammatory factors in the treatment group was lower than that in the control group (p<0.05). Loxofen sodium tablet is better than ibuprofen sustained-release capsule in alleviating the pain of periodontal pulp syndrome. Loxofen sodium tablets have obvious effects on improving pain and reducing the level of inflammatory factors in patients and its medication has recommended value.