Abstract
Skin patches containing micrometer-scale needles (“microneedles”) provide a safe, convenient, and pain-free approach for effective delivery of vaccines and pharmaceuticals. Paula T. Hammond, Darrell J. Irvine, and co-workers report on page 161 the design and use of a composite microneedle architecture for rapid cutaneous delivery and coordinated control over the release of antigen and adjuvant vaccine components for improved immunization in mice.
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