Abstract
Drug use problems are common worldwide. Nepal is a developing country with several drug use problems. The Drug and Therapeutics committee (DTC) in Manipal Teaching Hospital (MTH) has been playing a vital role in promoting rational use of medicines in the hospital. The DTC has banned several irrational fixed dose combinations and formulated several guidance regarding safe and effective use of medicines. The DTC in MTH has proven the importance of DTCs in developing countries like Nepal in improving rational use of medicines in hospitals settings.
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