Abstract
The in vitro adsorption characteristics and the inhibitory effect on drug absorption in man of commercial activated charcoal tablets and activated charcoal powder were determined, using phenylpropanolamine as the test drug. The rate and extent of drug adsorption on charcoal in tablets in vitro were much lower than on the charcoal powder. Under the conditions of the study, equal doses of charcoal tablets and powder reduced phenylpropanolamine absorption in healthy adult volunteers by 48 and 73%, respectively.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
