Abstract
Recent works on focused ultrasound (FUS) have shown great promise for cancer therapy. Researchers are continuously trying to improve system performance, which is resulting in an increased complexity that is more apparent when using multi-element phased array systems. This has led to significant efforts to reduce system size and cost by relying on system integration. Although ideas from other fields such as microwave antenna phased arrays can be adopted in FUS, the application requirements differ significantly since the frequency range used in FUS is much lower. In this paper, we review recent efforts to design efficient power monitoring, phase shifting and output driving techniques used specifically for high intensity focused ultrasound (HIFU).
Highlights
High-intensity focused ultrasound (HIFU) surgery allows energy to be focused deep in the body inducing noninvasive local temperature elevation that destroys the targeted tissue, while sparing the surrounding tissue
Since magnetic resonance imaging (MRI) can provide noninvasive temperature maps in real-time, the combination of MRI and high intensity focused ultrasound (HIFU) has proven to be very effective in the treatment of tumors [3]
MRI-guided HIFU has been studied for thermal ablation of pathological tissue, local drug delivery using thermosensitive micro-carriers and controlled transgene expression using thermosensitive promoters [4]
Summary
High-intensity focused ultrasound (HIFU) surgery allows energy to be focused deep in the body inducing noninvasive local temperature elevation that destroys the targeted tissue, while sparing the surrounding tissue. Sensors 2011, 11 temperature elevation [2] This noninvasive method can ablate tumors without the side-effects and complications associated with invasive surgery [3]. MRI-guided HIFU has been studied for thermal ablation of pathological tissue, local drug delivery using thermosensitive micro-carriers and controlled transgene expression using thermosensitive promoters [4]. As systems continue to grow in complexity and the demands to reduce system cost, weight, and size increase to allow for wider spread and portability, researchers are continuously trying to improve the existing power and control techniques. The various techniques used for phase shifting and output driving are discussed, in addition to some suggested areas of improvement
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