Abstract
BACKGROUND: The urolithiasis incidence in the Nizhny Novgorod Region exceeds the national average that determines the importance of analyzing the causes of its development and creating preventive measures. AIM: To evaluate the relationship between the urolithiasis incidence and drinking water composition consumed by the rural population of the Nizhny Novgorod Region. MATERIALS AND METHODS: A chemical analysis of drinking water was performed in 50 rural districts of the Nizhny Novgorod Region (a total of 61 samples). Water was taken from centralized water supply sources, artesian wells and boreholes, and springs. The relationship between the urolithiasis incidence and chemical composition measures of drinking water was assessed. RESULTS: Differences in the impurity content of drinking water were found between districts with different values of urolithiasis incidence. Exceeding the standard values for impurities specified in the Sanitary regulations and standards (SanPin) was most commonly detected in water from districts with the highest incidence of urolithiasis. An increase in the calcium/magnesium ratio was the most commonly noted in drinking water from these districts. In 41 (67.2%) of 61 samples, an increase of calcium level was detected. The hardness of drinking water was higher than the standard in 33.3–38.8% of samples depending on the water intake source. CONCLUSIONS: Drinking water with a high level of hardness and mineralization is one of the etiological factors for the development of urolithiasis in Nizhny Novgorod Region. In rural areas of this region with a high incidence of urolithiasis, the monitoring of the state of central water supply sources and the impurity content in drinking water should be intensified.
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