Abstract
Polygodial, isopolygodial, mukaadial and polygonone were isolated for the first time from Capsicodendron dinisii. Thus, with respect to drimane-type sesquiterpenoids of the Canellaceae, the close affinity of the South American genus Capsicodendron with the African genus Warburgia rather than the Madagascarian genus Cinnamosma is established.
Highlights
Stem bark of the South American arboreal species Capsicodendron dinisii (Schwacke) was reported to contain two cytotoxic compounds, cinnamodial (1d) and capsicodendrin (1e), besides three inactive compounds 6β-acetoxyisodrimenin (3a), ugandensolide (3b) and futronolide (3c)
Capsicodendron dinisii was collected near Curitiba and identified by Dr Gerdt Hatschbach
Partitioned between C6H14 and MeOH-H2O 19:1. Both solutions were evaporated to dryness, leading respectively to 18 and 38 g of residue. The latter partition fraction of the crude hexane extract was submitted to column chromatography (Si gel, 60 g)
Summary
Stem bark of the South American arboreal species Capsicodendron dinisii (Schwacke) was reported to contain two cytotoxic compounds, cinnamodial (1d) and capsicodendrin (1e), besides three inactive compounds 6β-acetoxyisodrimenin (3a), ugandensolide (3b) and futronolide (3c). The leaf-twig extract of the same species yielded another cytotoxic compound, cinnamosmolide (4c)[1]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
