Abstract
The drug sensing properties of procaine and berberine drug sensors based on ruthenium dioxide thin film were investigated. Ruthenium dioxide (RuO2) membrane prepared using a sputtering method was used as substrates for the drug sensors. The procaine and berberine drug sensors were prepared using a drug-saensitive membrane that measured the procaine and berberine concentration in a linear range from 1×10-2 M to 1×10-6 M and from 1×10-2 M to 1×10-7 M, respectively. The drift rates and hyteresis widths of these ruthenium dioxide based drug sensors were also investigated.
Highlights
In this decade, many researchers have used metal-oxide materials for pH sensors [1,2,3,4] or biosensors [5,6,7,8]
Chou et al [11] presented the procaine characteristics of the extended gate field effect transistor based on indium tin oxide (ITO) glass
The ruthenium dioxide thin film was deposited onto a silicon substrate using a sputtering system
Summary
Many researchers have used metal-oxide materials for pH sensors [1,2,3,4] or biosensors [5,6,7,8]. We used the ruthenium dioxide thin film as the substrate for procaine and berberine drug sensors. Molecular formula C13H20N2O2, is used in its hydrochloride form as a local anesthetic in medicine and dentistry It was first synthesized in 1905 by the German chemist Albert Einhorn. Chou et al [11] presented the procaine characteristics of the extended gate field effect transistor based on indium tin oxide (ITO) glass. Yang et al [14] reported on an optical sensor used for determining berberine Another berberine sensitive optical fiber sensor was prepared using a composite active material investigated by. The ruthenium dioxide thin film was deposited using a sputtering system and used for procaine and berberine drug sensors. The sensing and nonideal (drift rate and hysteresis width) characteristics of these drug sensors were investigated
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