Abstract
A series of novel chiral phosphanyl-oxazoline (PHOX) ligands possessing a cyclopropyl backbone were synthesized. It was shown that introduction of a strained cyclic fragment in the ligand platform helped restrict conformational fluctuations of the metallacycle and provided the catalyst with marked steric effects. It was demonstrated that insignificant alterations in the ligand structure had a dramatic influence on the stereochemical outcome of the intermolecular asymmetric Heck reaction.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
