Drainage volume on the postoperative first day after distal pancreatectomy predicts the occurrence of pancreatic fistula

Abstract

Objective To analyze the predictive factors of clinically relevant pancreatic fistula after distal pancreatectomy. Methods The perioperative data of 154 patients undergoing distal pancreatectomy at Anhui Provincial Hospital from Jan 2013 to Jan 2018 were retrospectively analyzed. 29 clinical factors were analyzed using SPSS 22.0. Results The univariate analysis of clinically relevant pancreatic fistula after distal pancreatectomy showed: body mass index, preoperative ALT level, pre- operation and first day after operation pre-albumin level, drain fluid volume on the first postoperative day, first postoperative day blood glucose level, combined with diabetes and ASA score were risk factors for clinically relevant pancreatic leakage (P<0.05). Multivariate analysis indicated that drain fluid volume on the first postoperative day and the preoperative ALT level were independent risk factors for clinically relevant pancreatic leakage (P<0.05). Conclusion The drainage volume on the first postoperative day can predict the occurrence of clinically relevant pancreatic fistula after distal pancreatectomy. Key words: Pancreatectomy; Pancreatic fistula; Risk factors