Draft Genome Sequences of Two Virulent Serotypes of Avian Pasteurella multocida.

Juan E Abrahante,Timothy J Johnson,Samuel K Maheswaran,Samuel S Hunter,Darrell O Bayles,Melissa J Hauglund,Fred M Tatum,Robert E Briggs

doi:10.1128/genomea.00058-12

Abstract

Here we report the draft genome sequences of two virulent avian strains of Pasteurella multocida. Comparative analyses of these genomes were done with the published genome sequence of avirulent P. multocida strain Pm70.

Highlights

We report the draft genome sequences of two virulent avian strains of Pasteurella multocida
Pasteurella multocida is the etiologic agent of fowl cholera, a highly contagious and severe disease of poultry causing significant mortality and morbidity throughout the world [1]
The sequences were assembled de novo with Newbler V2.6 (454 Life Sciences), and Pm70 was used as a reference strain for scaffolding; the resulting assembly generated 2.30 Mbp (40.21% GC, 24 contigs, 18 contigs Ͼ500 bp, N50 256,544) and 2.26 Mbp (40.30% GC, 39 contigs, 28 contigs Ͼ500 bp, N50 137,372) genomes for P1059 and X73, respectively

Summary

Introduction

We report the draft genome sequences of two virulent avian strains of Pasteurella multocida. Pasteurella multocida is the etiologic agent of fowl cholera, a highly contagious and severe disease of poultry causing significant mortality and morbidity throughout the world [1]. All types of poultry are susceptible to fowl cholera. Serotypes A:1, A:3, and A:3,4 are most commonly associated with fowl cholera in the United States [4].

Results

Conclusion