Draft Genome Sequences of Thermophiles Isolated from Yates Shaft, a Deep-Subsurface Environment.

Nitin K Singh,Rajesh K Sani,Kasthuri Venkateswaran,Courtney Carlson

doi:10.1128/genomea.00405-17

Abstract

ABSTRACTThe whole-genome sequences of seven thermophiles that could grow at >55°C, but not at 37°C, were generated. These thermophilic bacteria will play a useful role as model microorganisms, and analyzing their genomes will help to understand the observed production of novel bioactive compounds, including thermozymes and macromolecules.

Highlights

The whole-genome sequences of seven thermophiles that could grow at Ͼ55°C, but not at 37°C, were generated
UV resistance has been tested among large assortments of Bacillus spp. [3], but underlying genetic mechanisms of UV resistance have been not been reported in Geobacillus spp
The industrial applications of thermostable enzymes are widespread in diverse fields [5, 6]

Summary

Introduction

The whole-genome sequences of seven thermophiles that could grow at Ͼ55°C, but not at 37°C, were generated. Uncovering the molecular mechanisms of extremophiles, such as Geobacillus spp., will advance knowledge about the resistance of microorganisms to extreme extraterrestrial conditions (UV, etc.) and will play a crucial role in the field of astrobiology. (3), but underlying genetic mechanisms of UV resistance have been not been reported in Geobacillus spp.

Results

Conclusion