Abstract
Biotype 1 of Vibrio vulnificus, which causes severe invasive intestinal and wound infections, is split into two genotypes with all previously sequenced clinical isolates from the C genotypes. We report here the whole-genome sequencing of two clinical isolates and two closely linked oyster isolates from the E genotype for comparative studies.
Highlights
Biotype 1 of Vibrio vulnificus, which causes severe invasive intestinal and wound infections, is split into two genotypes with all previously sequenced clinical isolates from the C genotypes
Vibrio vulnificus is a seafood-associated pathogen found in coastal waters and can cause gastroenteritis, primary septicemia, and necrotizing fasciitis in food-borne and wound infections, respectively
Multilocus sequence typing (MLST) studies have a revealed a group of C-type strains that recently emerged from a cluster of E-type strains [10], leading us to hypothesize that these C-type strains have a genetic factor that is important for disease in humans that the E-type strains are lacking
Summary
Biotype 1 of Vibrio vulnificus, which causes severe invasive intestinal and wound infections, is split into two genotypes with all previously sequenced clinical isolates from the C genotypes. Vibrio vulnificus is a seafood-associated pathogen found in coastal waters and can cause gastroenteritis, primary septicemia, and necrotizing fasciitis in food-borne and wound infections, respectively. This pathogen is often found in association with oysters and other shellfish and is of particular risk to both human handlers and consumers of raw seafood [1].
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