Abstract
‘Treponema phagedenis’ is considered to be a key agent in the pathogenesis of bovine digital dermatitis, an infectious foot condition of economic and animal welfare importance. We hereby report the draft sequence of ‘T. phagedenis’ strain V1. The draft genome assembly consists of 51 scaffolds comprising 3,129,551 bp and a GC-content of 39.9 %. Putative pathogenicity related factors have been identified in the genome that can be used in future studies to gain insight into the pathogenic mechanisms of ‘T. phagedenis’.Electronic supplementary materialThe online version of this article (doi:10.1186/s40793-015-0059-0) contains supplementary material, which is available to authorized users.
Highlights
Digital dermatitis is a painful infection of the foot and is the leading cause of lameness in dairy cattle
A Treponema phylotype recently suggested being the same species as is the human commensal ‘Treponema phagedenis’ [5] which is considered to be a key agent in the pathogenesis of digital dermatitis [6,7,8,9]
The aim of the sequencing was to identify genes that are linked to pathogenicity and virulence in related bacteria, to strengthen the hypothesis that bacteria of the genus Treponema causes digital dermatitis in cattle
Summary
Draft genome sequence of ‘Treponema phagedenis’ strain V1, isolated from bovine digital dermatitis. Abstract ‘Treponema phagedenis’ is considered to be a key agent in the pathogenesis of bovine digital dermatitis, an infectious foot condition of economic and animal welfare importance. We hereby report the draft sequence of ‘T. phagedenis’ strain V1. The draft genome assembly consists of 51 scaffolds comprising 3,129,551 bp and a GC-content of 39.9 %. Putative pathogenicity related factors have been identified in the genome that can be used in future studies to gain insight into the pathogenic mechanisms of ‘T. phagedenis’
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