Abstract
Bacillus coagulans Unique IS-2 is a potential spore-forming probiotic that is commercially available on the market. The draft genome sequence presented here provides deep insight into the beneficial features of this strain for its safe use as a probiotic for various human and animal health applications.
Highlights
Bacillus coagulans Unique IS-2 is a potential spore-forming probiotic that is commercially available on the market
Bacillus coagulans Unique IS-2 has been isolated from healthy human feces [3] and has obtained a “no objection” rating from the U.S FDA to its generally regarded as safe (GRAS) status
The assembled genome sequence was annotated by the RAST annotation pipeline Web server [8, 9] and by NCBI Prokaryotic Genome Annotation Pipeline (PGAP) version 2.9. rRNAs and tRNAs were annotated using RNAmmer [10] and tRNAscan-SE [11], respectively
Summary
Bacillus coagulans Unique IS-2 is a potential spore-forming probiotic that is commercially available on the market. Among the lactic acid bacteria (LAB), spore formers have gained much attention due to their ability to withstand adverse conditions during production, downstream processing, storage, and gastric transit [1, 2]. Their high survival rates under hostile conditions make them the primary choice of probiotic candidates to consume either as oral medications or for incorporation into functional foods.
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