Abstract

Leishmania tarentolae is a protozoan parasite of lizards and is nonpathogenic to mammals. Genome information for the nonpathogenic species will facilitate an understanding of the pathology caused by species pathogenic to mammals. Here, we report resequencing of the L. tarentolae genome with a single-molecule real-time (SMRT) sequencer to provide a more complete genome assembly.

Highlights

  • Protozoan parasites of the genus Leishmania are causative agents of leishmaniasis

  • There are around 20 species causing the disease in humans, which can be mainly classified into three forms, namely, cutaneous leishmaniasis, mucocutaneous leishmaniasis, and visceral leishmaniasis, depending on the infecting species

  • The genetic information is useful for identification of leishmanial targets good for the development of drugs, vaccines, or diagnostic tests

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Summary

Introduction

Protozoan parasites of the genus Leishmania are causative agents of leishmaniasis. There are around 20 species causing the disease in humans, which can be mainly classified into three forms, namely, cutaneous leishmaniasis, mucocutaneous leishmaniasis, and visceral leishmaniasis, depending on the infecting species. Leishmania tarentolae is a protozoan parasite of lizards and is nonpathogenic to mammals.

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