Draft Genome Sequence of Environmental Vibrio cholerae 2012EL-1759 with Similarities to the V. cholerae O1 Classical Biotype.

Lee S Katz,Vincent R Hill,Amy Kahler,E Fidelma Boyd,Cheryl L Tarr,Maryann Turnsek

doi:10.1128/genomea.00617-14

Abstract

Vibrio cholerae 2012EL-1759 is an environmental isolate from Haiti that was recovered in 2012 during a cholera outbreak. The genomic backbone is similar to that of the prototypical V. cholerae O1 classical biotype strain O395, and it carries the Vibrio pathogenicity islands (VPI-1 and VPI-2) and a cholera toxin (CTX) prephage.

Highlights

Vibrio cholerae 2012EL-1759 is an environmental isolate from Haiti that was recovered in 2012 during a cholera outbreak
Cholera toxin-producing Vibrio cholerae O1 was first detected in Haiti in October 2010, and both the epidemiological and genomic data are consistent with the notion of a single exogenous source for the ongoing outbreak [1,2,3]
In addition to recovering the toxigenic epidemic strain, nontoxigenic non-O1/O139 V. cholerae isolates that were positive by PCR for tcpA were recovered from Haitian waters (Kahler, Haley, Chen, Mull, Tarr, Turnsek, Katz, Humphrys, Freeman, Boncy, Colwell, Huq, and Hill, unpublished data)

Summary

Introduction

Vibrio cholerae 2012EL-1759 is an environmental isolate from Haiti that was recovered in 2012 during a cholera outbreak. Cholera toxin-producing Vibrio cholerae O1 was first detected in Haiti in October 2010, and both the epidemiological and genomic data are consistent with the notion of a single exogenous source for the ongoing outbreak [1,2,3].

Results

Conclusion