Draft Genome Sequence of a Multidrug-Resistant Acinetobacter baumannii Strain from Chile.

Andrés Opazo,Sebastian G B Amyes,Gerardo González-Rocha,Helia Bello-Toledo,Celia Lima,Patricia García,Bruno S Lopes,Mariana Domínguez Yévenes

doi:10.1128/genomea.00687-15

Abstract

Acinetobacter baumannii strain Ab5 was isolated in the year 2007 in Chile, being one of the first multidrug-resistant (MDR) cases reported in the country. Here, we present the very first draft genome sequence of an MDR Chilean strain, which shows the presence of diverse resistance and acquired virulence genes.

Highlights

Acinetobacter baumannii is a nosocomial pathogen normally classified as multidrug resistant (MDR)
The number of MDR A. baumannii isolates has increased in the last few years, making it a difficult microorganism to treat [1, 2], as infections caused by it are associated with high rates of mortality and long periods of hospitalization [3]
The rates of Acinetobacter species MDR isolates in Latin America have increased lately, as resistance to imipenem in Chile increased from 0.0% during 1997 to 1999, to 47.4% in the 2008 to 2010 period [4], and 65.8% in 2014 (Antibiotic Resistant Group from Chilean Society for Infectious Diseases, personal communication)

Summary

Introduction

Acinetobacter baumannii is a nosocomial pathogen normally classified as multidrug resistant (MDR). The number of MDR A. baumannii isolates has increased in the last few years, making it a difficult microorganism to treat [1, 2], as infections caused by it are associated with high rates of mortality and long periods of hospitalization [3]. The rates of Acinetobacter species MDR isolates in Latin America have increased lately, as resistance to imipenem in Chile increased from 0.0% during 1997 to 1999, to 47.4% in the 2008 to 2010 period [4], and 65.8% in 2014 (Antibiotic Resistant Group from Chilean Society for Infectious Diseases, personal communication).

Results

Conclusion