Abstract
Here, we report the draft genome sequence of Bacteroides fragilis strain Z&Z143, a metronidazole-resistant bacterium isolated from a blood culture from an Ecuadorian patient hospitalized in a medical institution in Quito, Ecuador. We describe a new variant of the nim genes, which is associated with metronidazole resistance.
Highlights
Bacteroides fragilis is a predominant organism in the colon microbiota (1)
The draft genome of metronidazole-resistant B. fragilis Z&Z143 has a length of 5,158,698 bp, with an N50 value of 196,742 bp, genome coverage of 200.0ϫ, and GϩC content of 43.1%
A total of 4,320 protein-coding genes and 71 RNA-coding sequences were detected after manual inspection of the annotations using the NCBI Prokaryotic Genome Annotation Pipeline (PGAP) (10)
Summary
Bacteroides fragilis is a predominant organism in the colon microbiota (1). It is one of the most frequently isolated species from clinical infections and bacteremia (2). The isolated B. fragilis strain was characterized according to its phenotypic and genotyping resistance (Table 1). The draft genome of metronidazole-resistant B. fragilis Z&Z143 has a length of 5,158,698 bp, with an N50 value of 196,742 bp, genome coverage of 200.0ϫ, and GϩC content of 43.1%.
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