Abstract
Dracocephalum palmatum S. and Dracocephalum ruyschiana L. contain a large number of target analytes, which are biologically active compounds. High performance liquid chromatography (HPLC) in combination with an ion trap (tandem mass spectrometry) was used to identify target analytes in extracts of D. palmatum S. and D. ruyschiana L. originating from Yakutia. The results of initial studies revealed the presence of 114 compounds, of which 92 were identified for the first time in the genus Dracocephalum. New identified metabolites belonged to 17 classes, including 16 phenolic acids and their conjugates, 18 flavones, 5 flavonols, 2 flavan-3-ols, 1 flavanone, 2 stilbenes, 10 anthocyanins, 1 condensed tannin, 2 lignans, 6 carotenoids, 3 oxylipins, 2 amino acids, 3 sceletium alkaloids, 3 carboxylic acids, 8 fatty acids, 1 sterol, and 3 terpenes, along with 6 miscellaneous compounds. It was shown that extracts of D. palmatum are richer in the spectrum of polyphenolic compounds compared with extracts of D. ruyschiana, according to a study of the presence of these compounds in extracts, based on the results of mass spectrometric studies.
Highlights
The genus Dracocephalum L. is represented on the territory of the Republic of Sakha (Yakutia) by five species—Dracocephalum jacutense Peschkova, D. nutansL., D. palmatum Stephan, D. ruyschiana L., and D. stellerianum Hiltebr [1]
Extracts of D. palmatum S. and D. ruyschiana L. were analyzed by an High performance liquid chromatography (HPLC)–MS/MS
A total of 114 compounds were identified in extracts of D. palmatum and D. ruyschiana, and 92 compounds were identified for the first time in the genus Dracocephalum
Summary
The genus Dracocephalum L. (family Lamiaceae) is represented on the territory of the Republic of Sakha (Yakutia) by five species—Dracocephalum jacutense Peschkova, D. nutansL., D. palmatum Stephan, D. ruyschiana L., and D. stellerianum Hiltebr [1]. (family Lamiaceae) is represented on the territory of the Republic of Sakha (Yakutia) by five species—Dracocephalum jacutense Peschkova, D. nutans. L., D. palmatum Stephan, D. ruyschiana L., and D. stellerianum Hiltebr [1]. These are perennial herbaceous plants, differing in both origin and habitat and belonging to the divisions of vegetation cover. The ranges of Dracocephalum are unequal, from extremely small A total of 23 compounds (phenylpropanoids, coumarins, flavonoids, and triterpenes) were isolated from a crude alcoholic extract of the aerial parts of Dracocephalum palmatum in studies by Olennikov et al (2013) [4]. A research by Kim et al (2020) aimed to evaluate the tumor suppressive effect of D. palmatum extract in diffuse large B cell lymphoma (DLBCL)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
