Abstract
AbstractIn this report, we describe an application of ethyl difluoroacetate‐substituted allylic sulfides in Doyle‐Kirmse rearrangement reactions that allow efficient access to valuable fluorinated small molecules with applications in total synthesis and drug discovery. A cheap and readily available rhodium catalyst or – in a metal‐free variant – visible light was used to generate a carbene intermediate to access rearrangement reactions in high yield.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
