Abstract
A retrospective study was undertaken on patients with multiprimaries associated with vulva carcinoma, analyzing in particular 33 patients with double epidermoid primaries of the vulva and cervix. It is noted that 20.8% of patients with vulvar carcinoma had a second primary; this occurred more frequently in intraepithelial (33.3%) than in invasive (16.0%) vulvar carcinoma. While the commonest second primary is located in the cervix, this association appears significant only in patients with intraepithelial (22.5%), but not in invasive (7.9%), vulvar carcinoma. The incidences previously reported in the literature are also reviewed for comparison.
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