Abstract
AbstractDescribed herein is an organoborane‐catalysed consecutive borylative reduction of quinolines and isoquinolines to furnish tetrahydro(iso)quinolines bearing a C(sp3)−B bond β to the nitrogen atom. The installed C−B bond is oxidatively transformed to the hydroxy group in one pot. The present double hydroboration is proposed to proceed via a stepwise ionic mechanism involving a boronium ion. The stereo‐outcome was found to be dependent on the position (C2 vs C4) of the substituents in quinolines.magnified image
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