Abstract

Endoscopic submucosal dissection (ESD) of colonic lesions can be quite challenging owing to the very thin colon wall1 and limited expandability of the colonic submucosal space, which is in stark contrast to the forgiving esophageal and stomach submucosa.1 In addition, the colonic muscularis propria can be easily disrupted with inadvertent cauterization by the dissection knife or simply via pressure from the endoscope. Colonic looping and the lesion’s location behind folds or around flexures can add to the difficulty of the procedure.

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