Abstract
Two immunoassays, dot enzyme-linked immunosorbent assay (dot-ELISA) and dot-dye immunoassay (dot-DIA), using soluble egg antigen and keyhole limpet haemocyanin as antigens, were evaluated for the serological differentiation of 25 acute and 37 chronic patients infected with Schistosoma mansoni and 20 non-infected individuals, in comparison with ELISA. Efficiency was 92·7%, 90·2%, and 89·0% for ELISA, dot-ELISA and dot-DIA, respectively. Dipstick dot-ELISA and dot-DIA are described and shown to be reliable, cheap and simple methods for the serological differentiation of acute and chronic schistosomiasis.
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Schedule a callMore From: Transactions of the Royal Society of Tropical Medicine and Hygiene
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