Abstract
Postoperative radiotherapy for glioma has been shown benefit to improve survival with increased radiation doses. Dose from external beam radiotherapy is limited by normal brain toxicity. Brachytherapy can deliver higher radiation doses contained within short distance near the implants. However, traditional solid source implants require a second invasive procedure, and often fail to tailor the dose distribution to the target volume. One novel approach is to use radiolabeled target molecules to penetrate and deliver localized radiation to the tumor cells.
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