Abstract
IntroductionThe objective is to report the dosimetry and safety profiles of the first fully automatized rotating gamma ray unit for intracranial radiosurgery in America.MethodsDosimetry tests were conducted by our institution using the standard of examination and calibration and the Intelligent γ Radiometer of the China Research Institute of Measurement. The phantom and dosimetry tests were performed by the Outreach Physics Section of MD Anderson Cancer Center and the Anchorage Radiation Therapy Center using the Radiation Therapy Oncology Group (RTOG) radiosurgery quality assurance guidelines. Clinically, 233 patients were treated.ResultsMechanical precision was 0.16 mm and the offset registered at the phantom on all axes was 0.0. The ratio of the dose to the center was 0.97 (0.95-1.05), the ratio of the treated volume was 0.95 (0.75-1.25), the ratio of the measured treated volume to the volume of the target was 1.29 (1.00-2.00), the ratio of the minimal dose to the dose prescribed was 1.05 (>0.90), with a treated volume of 0.95 (0.75-1.25) and a minimum dose to target of 1.05 (>0.90). The dose rate at loading was 3.89 Gy per minute. None of the patients treated experienced severe complications.ConclusionsThe dosimetry studies are compliant with quality assurance standards for intracranial radiosurgery.
Highlights
The objective is to report the dosimetry and safety profiles of the first fully automatized rotating gamma ray unit for intracranial radiosurgery in America
The dosimetry studies are compliant with quality assurance standards for intracranial radiosurgery
Intracranial stereotactic radiosurgery was developed by Lars Leksell and the tool he and his group developed: the Gamma knife
Summary
The current investigation was carried out from March 2014 to January 2017 During this period, 30 cobalt 60 sources were loaded on a fully automated, rotating gamma-ray system called Infini. Dosimetry studies were carried out by the institution where Infini was installed and three outside institutions participated in a phantom test analysis before the first patient was treated. Infini is a fully automated, rotating gamma-ray machine designed for intracranial stereotactic radiosurgery (Figure 1). It uses 30 rotating cobalt 60 sources that revolve with regards to the mechanical isocenter using a multisource, non-isometric spiral focusing method. It has an independent beam switch that can turn on or off the passage of radiation every 5 degrees
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