Abstract
Dosimetric Study on the Consequences of Replacing the mMLC Collimator Used for Intracranial SRS by an Integrated MLC-160
Highlights
Stereotactic Radiosurgery (SRS) is a treatment technique characterized by the administration of high doses of radiation in a single fraction with high accuracy to a small and well-defined intracranial target, while limiting the dose to surrounding normal tissues [1].In the early development of linear accelerator-based (LINAC)systems, circular collimators of different diameters coupled to the LINAC were used and the SRS treatment was performed with multiple convergent and non coplanar arcs [2,3]
The characteristics associated with the multileaf collimator (MLC)-160 system contributed to a poorer dose conformity, mainly for irregular shaped or small lesions and for lesions at close proximity to organs at risk (OARs)
The mMLC associated with the dynamic arc technique yields dosimetric benefits in radiosurgery
Summary
Stereotactic Radiosurgery (SRS) is a treatment technique characterized by the administration of high doses of radiation in a single fraction with high accuracy to a small and well-defined intracranial target, while limiting the dose to surrounding normal tissues [1].In the early development of linear accelerator-based (LINAC)systems, circular collimators of different diameters coupled to the LINAC were used and the SRS treatment was performed with multiple convergent and non coplanar arcs [2,3]. Et al [7] analysed the impact of the MLC leaf width on stereotactic radiosurgery and 3D conformal radiotherapy treatment plans, using 1.7, 3 and 10 mm leaf width MLC systems. They showed that for radiosurgery treated lesions, the 1.7 and 3 mm leaf width allowed to comply the RTOG treatment planning guidelines for SRS, in most cases. Tanyi, et al [10] performed a dosimetric comparison between MLC systems with 2.5 mm and 5 mm leaf width for the SRS treatment of 68 intracranial lesions and demonstrated small dosimetric benefits of the 2.5 mm leaf width MLC system over the 5 mm leaf width system
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