Abstract
Normoxic Polyacrylamide Gels, or nPAGs, are 3D gel dosimeters that measure dose through the process of radiation-induced polymerization. Two nPAG formulae are DEFGEL and PAGAT, which are very similar, but differ mainly due to different weight fractions of monomers. The dosimetric resolutions of the two formulae when paired with a Spin-Echo (SE) MRI sequence and a monoexponential fit were compared over a range of 0-15 Gy. It was found that in the dose range 0-6 Gy the PAGAT formula generally showed a much finer dose resolution, while the DEFGEL formula showed a finer resolution from 8-15 Gy.
Highlights
Gel dosimeters such as polyacrylamide gels (PAGs) and normoxic polyacrylamide gels can measure 3D dose distributions, while maintaining tissue equivalence, dose rate independence, and angular independence [1,2,3]
2.1 Gel Fabrication & Irradiation Twelve gel dosimeters were fabricated in-house, six using the DEFGEL formula described by Yeo et al and six using the PAGAT formula described by Venning et al [1,5]
The measured mean R2 values and their standard deviations are shown in Table 2 and the resultant monoexponential fits are shown in Figure 1 and Table 3
Summary
Gel dosimeters such as polyacrylamide gels (PAGs) and normoxic polyacrylamide gels (nPAGs) can measure 3D dose distributions, while maintaining tissue equivalence, dose rate independence, and angular independence [1,2,3]. This family of gel dosimeters operates through the radiation-induced polymerization of the monomer acrylamide and the cross linking monomer N,N’-methylenebis-acrylamide (Bis). The DEFGEL formula has a 6% monomer fraction by weight, while the PAGAT formula has 9% This difference in monomers concentration causes each dosimeter to result in different dose responses and dose response calibrations [5]. The goal of this investigation is to compare the dose response of both gel formulae through an analysis of the dose resolutions of the gels over a range of 0-15 Gy
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
