Abstract
The anti-edema effect of intravenous glycerol, infused at a constant rate, is delineated in a patient with raised cerebrospinal fluid pressure caused by trauma. There is no one critical blood level necessary for the therapeutic action. Instead, increasing the blood glycerol level results in a progressively greater anti-edema effect. Hemolysis does not occur if the infusion rate of 10 percent glycerol in 0.45 saline is less than 4.5 ml per minute. The brain dehydration effect begins within 30 minutes and continues for up to nine hours after cessation of the infusion. Because of a continuing rise of the glycerol level during a rate-fixed infusion, it is suggested that administration be semicontinuous rather than continuous. No rebound rehydration is observed. Water and electrolyte losses are minimal.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
