Abstract
IN mice the mutation rate in irradiated spermatogonia is less at low dose rates (0.009 r./min) than at high dose rates (90 r./min and more)1,2. Tazima et al.3 have observed that the mutation frequency for chronic irradiation is higher than that for acute irradiation when the silkworms are irradiated about 7 days after hatching. To explain such a peculiar dose rate effect, various hypotheses3,4 have been proposed. In this communication, the effect of dose rate on death and repopulation of spermatogonia is cytologically analysed with particular reference to the possibility of selective elimination of the cells after exposure to different dose rates of radiation. The spermatogonia of the silkworm are readily killed by acute irradiation5,6.
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