Abstract
Creatine excretion in urine of rats after whole-body exposure to various doses of x rays (25 to 1000 r) and after sham-irradiation was determined. Although creatinuria was observed at all levels of exposure, the degree was dependent on the dose. Creatinuria lasted from 3 to 16 days after exposure. In the intermediate dose range a second rise in the excretion of creatine was observed during the second week after exposure. The average creatine excretion during the initial 4 days after exposure varied linearly with the dose up to 650 r.
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