Dose confirmation study of a 10 g liter1 non‐aqueous injectable formulation of moxidectin against naturally acquired infestations of cattle lice on cattle in New York

Abstract

This study demonstrated that a moxidectin 10 g liter−1 non-aqueous injectable formulation, injected subcutaneously in cattle at a dose of either 0.2 or 0.3 mg moxidectin kg−1 body weight was safe and highly effective in the almost complete elimination (>99% efficacy) for 56 days of both the nymphal and adult stages of naturally acquired infestations of the three species of sucking lice commonly found on cattle, Haematopinus eurysternus (Nitzsch), Linognathus vituli (L), and Solenopotes capillatus (Enderlein). The level of efficacy was never greater than 90% with either dose against Bovicola bovis (L). No adverse effects were noted on cattle from either of the moxidectin doses used. © 1999 Society of Chemical Industry