Abstract

The food consumption of Charles River male rats with dorsomedial amygdala lesions was compared with sham operates and normal controls on four tests spanning a 65-day postsurgery period. Following 24-h food deprivation (18- and 65-day postsurgery tests), lesioned animals ate significantly less than the other two groups (p <.01). Although 24-h food and water deprivation (35- and 50-day postsurgery tests) increased the absolute level of food consumption in all groups, the relative magnitude of the feeding deficit in lesioned animals remained approximately the same (p <.01). The results suggest that hypotheses which stress the “temporary deficit” nature of lesion effects do not adequately explain the changes in feeding following dorsomedial amygdala damage.

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