Abstract
Dynamic in vivo changes in dorsal cochlear nucleus blood flow during pure-tone stimulation were assessed with intravital microscopy. Subjects were stimulated with 5-, 10-, or 15-kHz pure tones at 70, 80, and 90 dB sound pressure level. Measurements in red blood cell velocity and vessel diameter were made in capillaries overlying the 10-kHz isofrequency band of the dorsal cochlear nucleus. Stimulation with 10 kHz induced intensity-dependent increases in local blood flow in the 10-kHz isofrequency band of the dorsal cochlear nucleus. Stimulation with 5 kHz and 15 kHz, frequencies represented in remote locations on the dorsal cochlear nucleus surface, did not significantly alter blood flow in the defined 10-kHz isofrequency band. These data demonstrate a direct relationship between spectral and intensity-dependent pure-tone stimulation of the dorsal cochlear nucleus and increases in local blood flow. These findings suggest that tonal stimulation of the dorsal cochlear nucleus induces an increase in local metabolic demands with resultant rapid blood flow increases. (Otolaryngol Head Neck Surg 1996;114:613-9.)
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
