Abstract
EDITOR,--The use of dornase alfa has been a topic of recent controversy.1 2 3 South and West region's development and evaluation committee of senior clinicians supported by a research review team undertook to determine the drug's cost effectiveness on the basis of the published evidence.4 The net cost (total costs less savings) to the NHS of prescribing a daily dose of 2.5 mg of dornase alfa to patients with cystic fibrosis in the former Wessex Regional Health Authority, excluding children under …
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