Abstract
Mycobacterium tuberculosis (MTB) is a major microbial pathogen that threatens global health. The WHO has estimated about 9 million new tuberculosis (TB) cases and around 1.5 million deaths due to TB in the year 2013 (World Health Organization, 2014). In MTB-infected individuals, bacteria may exist in a dormant state for lengthy periods without causing disease symptoms, or may finally start multiplying and evading immune control, resulting in active TB in 5–10% of infected cases. At present, factors that promote progression from latent tuberculosis infection (LTBI) to disease are not totally understood. Therefore, management of LTBI plays a significant role for TB disease control given that quiescent bacilli are a big reservoir of potential TB cases.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
