Doppler of Renal Segmental Artery Resistive Index in Diabetic Patients

Mavra Khaliq ,Anjum Tazeen ,Naveed Asad ,Yousaf Gillani ,Umm E Farwa Latif ,Iqra Nawaz ,Ramsha Javaid ,Shereen Idrees

doi:10.7176/jhmn/82-03

Abstract

Background: Diabetic nephropathy affects 40 percent of patients with type I diabetes mellitus. It carries a poor prognosis when fully developed, where the estimated death rate is approximately 40-100 times that of non-diabetics. Vascular resistivity evaluation at multiple points of renal parenchyma can indicate structural or functional changes within the kidneys and can provide useful diagnostic and prognostic information. Objective: The goal of the research was to use renal artery Doppler to evaluate the mean renal resistivity index in patients with Diabetes Mellitus. Methodology: The research was initiated with the approval of the University of Lahore Ethical Committee. In this study, all the patients were registered after signing the informed consent form. Toshiba Xario was used with a convex probe of frequency of 3-5 MHz. Renal Resistive Index (RRI) was evaluated and sonographic data was kept in the ultrasound unit. The Statistical package for Social Sciencies version 24 was used for analysing the data. Results: Among 97 patients, there were 66 females and 31 males of which 50 patients were with Diabetes and 47 were normal. In the result of our study it was seen that renal resistive index significantly increases in patients with Diabetes Mellitus. Conclusion: In conclusion, renal resistive index (RRI) levels were high in patients with Diabetes Mellitus showing positive correlation of RRI values Keywords: Diabetic nephropathy, Renal resistive index, Chronic kidney disease DOI: 10.7176/JHMN/82-03 Publication date: November 30 th 2020

Highlights

Diabetes mellitus is one of the most common chronic illnesses
Our study is focused on doppler of renal segmental artery resistive index in diabetic patients since Doppler US is a non invasive, less costly, available and repeatable modality that can help in diagnosis and assesssment of severity of renal disease
Diabetes mellitus type 2 (DM 2) is one of the most frequent starting point of kidney dysfunction and the progression of long standing renal disease The incidence is increasing day by day in our country because there is lack of proper screening and treatment.Due to poor socioecnomic condition of most patients they cannot afford the expense of costly renal function tests on a regular basis

Summary

Introduction

Diabetes mellitus is one of the most common chronic illnesses. The global prevalence of adult diabetes (20-79 years of age) was 6.4% in 2010 affecting 285 million adults and is expected to increase to 7.7% in 2030 affecting 439 million adults.[1]. An evaluated 3.4 million people died from high levels of fasting blood sugar in 2004.4 In undeveloped countries due to diabetes, more than 80 percent of deaths occur.[5]. Diabetic nephropathy affects 40 percent of patients with type I diabetes mellitus It carries a poor prognosis when fully developed, where the estimated death rate is approximately 40-100 times that of nondiabetics. Objective: The goal of the research was to use renal artery Doppler to evaluate the mean renal resistivity index in patients with Diabetes Mellitus. In the result of our study it was seen that renal resistive index significantly increases in patients with Diabetes Mellitus.

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