Abstract
We present a description of a new software package, ‘dopOSCCI’, which summarises data from experimental studies where functional transcranial Doppler ultrasonography (fTCD) is used to compare hemispheric rates of blood flow in order to assess lateralization of a cognitive process. The software provides a graphical user interface to summarise analogue and digital data collected using Multi-Dop Doppler Ultrasound devices (DWL Multidop T2: manufacturer, DWL Elektronische Systeme, Singen, Germany). The unique aspects of dopOSCCI allow multi-file processing, multi-event marker processing, behavioural and multi-session summaries, image file data visualization, and tab-delimited output files which includes split-half, single-trial summaries and data quality variables. The Matlab based software is available under the GNU GPL license and can be accessed online at https://databank.ora.ox.ac.uk/general/datasets/dopOSCCI, the Oxford University DataBank.
Highlights
Functional transcranial Doppler ultrasonography is a non-invasive imaging technique which assesses changes in blood flow velocity in the cerebral arteries with high temporal resolution (Aaslid et al, 1982)
The standard functional transcranial Doppler ultrasonography (fTCD) paradigm for the assessment of language lateralisation is word generation introduced by Knecht et al (1996,1998b), which has been used successfully in fMRI (Benson et al, 1999)
All necessary functionality can be achieved through the interface; knowledge of Matlab is not necessary to use the software
Summary
Functional transcranial Doppler ultrasonography (fTCD) is a non-invasive imaging technique which assesses changes in blood flow velocity in the cerebral arteries with high temporal resolution (Aaslid et al, 1982). While more complex techniques (e.g., functional Magnetic Resonance Imaging, fMRI or Magnetoencephalography) allow for relatively precise localization of activity, fTCD measures blood flow in a particular artery. One common application for fTCD is the assessment of language lateralization (for a review of applications see Stroobant and Vingerhoets, 2000), which may be for pre-surgical determination or psychological research. Functional lateralization is assessed by concurrent measurement of blood flow velocity in homologue cerebral arteries in the two hemispheres. The recorded blood flow velocity can be analysed to determine an individual’s cerebral dominance for a particular task (for a detailed account see Ringelstein et al, 1990). Language tasks have been developed for children (Lohmann et al, 2005; Bishop et al, 2009) and a video description of Bishop et al.’s technique is available (Bishop et al, 2010)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
