Abstract
1) Exposure of pedal ganglia to the tricyclic antidepressant imipramine lowered the total endogenous dopamine concentration by 27 %.2) Field-stimulation of pedal ganglia labelled with 3H-dopamine caused release of the amine.3) Release of 3H-dopamine from field-stimulated pedal ganglia may be potentiated by imipramine.4) Newly accumulated 3H-dopamine mixes with the unlabeled endogenous dopamine in the ganglion and is not preferentially released.
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