Abstract
Initially the electrochemical behavior of dopamine (DA) and uric acid (UA) in different supporting electrolytes was investigated. It was found that the most suitable supporting electrolytes were pH 2.5 H2SO4 and pH 7.2 phosphate buffer. The analysis of DA and UA in acidic medium was carried out by the use of their oxidation peaks observed at +0.480 V and +0.620 V, respectively. The analysis of the phosphate buffer medium were carried out by the use of the oxidation peaks of DA and UA appeared at +0.140 V and +0.270 V, respectively. The studies carried out with different [DA] / [UA] ratios gave acceptable results for both media. The synthetic sample was analyzed. The error was -0.41 % for DA and 0.27 % for UA in acidic media and -0.61 % for DA and -0.14 % for UA in basic media. The limits of detection (LOD) were found as 2.16 A 10-8 M and 4.14 A 10-8 M in acidic media, 2.28 A 10-8 M and 2.13 A 10-8 M in basic media for DA and UA, respectively.
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