Abstract
The chemosterilizing effects of low concentrations of thiotepa on Aedes aegypti were tested. Three-day-old males were treated with 0.001, 0.0025, and 0.005% thiotepa by allowing them to feed freely for 5 days on sugar cubes containing the chemical mutagen. Egg production, percent hatchability, and productivity (average number of adult progeny surviving over 1 week) were used to assess mutagenic effects. Although egg production was higher in thiotepa-treated groups, the effects were not statistically significant when compared to untreated populations. By contrast, hatchability and the mean number of F1 progeny were reduced at concentrations of 0.001 and 0.0025%. Male sterility was induced with 0.005% thiotepa.
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