Abstract
Peri-implant mucositis is a pathological condition characterized by an inflammatory process in the peri-implant soft tissues. Progression to peri-implantitis takes place in case of peri-implant bone resorption. Recently, an aid for non-surgical treatment by mechanical debridement (SRP) has been identified in probiotics. As there are no recent studies regarding their use for peri-implant mucositis, the aim of this study was to test a new postbiotic gel for this clinical condition. A split-mouth randomized clinical trial was performed. Twenty patients undergoing SRP were randomly assigned to two treatments based on the following oral gels: chlorhexidine-based Curasept Periodontal Gel (Group 1) and postbiotic-based Biorepair Parodontgel Intensive (Group 2). At baseline (T0) and after three (T1) and six (T2) months, the following peri-implant mucositis indexes were recorded: Probing Pocket Depth (PPD), Plaque Index (PI), Gingival Bleeding Index (GBI), Bleeding Score (BS), Marginal Mucosal Condition (MMC). A significant decrease is reported for both postbiotic and chlorhexidine for all peri-implant mucositis indices studied. Quite the opposite, no significant variation was present in intergroup comparisons. Greater improvements for BS, GBI and MMC inflammatory indices of the postbiotic gel compared to chlorhexidine suggest the importance of further studies to investigate the relevance of the product alone.
Highlights
Introduction iationsDental prosthetic rehabilitation supported by osseo-integrated implants has increased considerably in recent decades [1]
As the number of implants positioned rises, so does the frequency of relative comAs the number of implants positioned rises, so does the frequency of relative plications leading to implant loss: loss of osseointegration; implant fracture; fracture of complications leading to implant loss: loss of osseointegration; implant fracture; fracture the screw connecting the abutment to the implant; fracture of the screw connecting the of the screw connecting the abutment to the implant; fracture of the screw connecting the crown to the abutment; peri-implant mucositis; and crown to the abutment; peri-implant mucositis; and peri-implantitis [38]
This study shows that the use of postbiotic gels is effective in reducing inflammatory indices
Summary
Dental prosthetic rehabilitation supported by osseo-integrated implants has increased considerably in recent decades [1]. The biological complications that can occur with them, mainly infectious-inflammatory processes, raise great interest in contemporary dentistry [2]. It is possible to recognize two clinical conditions: peri-implant mucositis and, subsequently, peri-implantitis [3]. Peri-implant mucositis is a pathological condition characterized by the development of an inflammatory process in the soft tissues surrounding the implant surfaces, without affecting the bone structure in which the implant is located [2]. If peri-implant bone resorption is associated, there is a progression into peri-implantitis, leading to implant loss and, failure of the prosthetic work [4,5]. From a clinical point of view, the diagnosis of peri-implant mucositis requires the presence of bleeding and/or suppuration on gentle probing and Licensee MDPI, Basel, Switzerland
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