Abstract

Extensive literature exists regarding control of hypertension in patients with coronary artery disease (CAD). However, debate continues with respect to the effects of excessive lowering of the diastolic blood pressure. This study is a secondary analysis of a large cohort of patients from the International Verapamil-Trandolapril Study (INVEST), in which the authors examined the data to determine if low diastolic blood pressure is associated with increased morbidity and mortality in patients with CAD and hypertension.

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