Abstract
BackgroundObesity is a growing health issue in the Western world. Obesity, as part of the metabolic syndrome adds to the morbidity and mortality. The incidence of diabetes and hypertension, two primary etiological factors for chronic renal failure, is significantly higher with obesity. We report a case with morbid obesity whose renal function was stabilized with aggressive management of his obesity.Case reportA 43-year old morbidly obese Caucasian male was referred for evaluation of his chronic renal failure. He had been hypertensive with well controlled blood pressure with a body mass index of 46 and a baseline serum creatinine of 4.3 mg/dl (estimated glomerular filtration rate of 16 ml/min). He had failed all conservative attempts at weight reduction and hence was referred for a gastric by-pass surgery. Following the bariatric surgery he had approximately 90 lbs. weight loss over 8-months and his serum creatinine stabilized to 4.0 mg/dl.ConclusionObesity appears to be an independent risk factor for renal failure. Targeting obesity is beneficial not only for better control of hypertension and diabetes, but also possibly helps stabilization of chronic kidney failure.
Highlights
Obesity is a growing health issue in the Western world
Obesity is associated with increase in morbidity, mortality and reduction in life expectancy [2], and leads to increase in the incidence of diabetes [3], hypertension [4], dyslipidemia and coronary artery disease [5]. Both diabetes and hypertension together account for approximately 70% of end-stage renal disease (ESRD)
Kidney disease has not yet been recognized as a major component of this metabolic syndrome, accumulating evidence suggests that even in non-diabetic obese patients, there is some degree of renal dysfunction that can lead to more serious injury to
Summary
Obesity is a growing health issue in the Western world. Obesity, as part of the metabolic syndrome adds to the morbidity and mortality. Targeting obesity is beneficial for better control of hypertension and diabetes, and possibly helps stabilization of chronic kidney failure.
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