Abstract

Liver cirrhosis favors portal hypertension which causes complications like variceal bleeding, therapy-refractory ascites, and hepatorenal syndrome. Transjugular intrahepatic portosystemic shunt (TIPS) is used for the treatment of portal hypertension. However, parenchymal portal venous flow after TIPS insertion is reduced. TIPS therefore might induce ischemic liver injury which has been discussed to favor hepatocarcinogenesis resulting in the development of hepatocellular cancer (HCC).

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