Abstract

To the Editor. —The article on sinusitis by Williams and Simel1is a valuable contribution, but the authors overstate their case in two areas. First, they cite two studies of maxillary sinusitis2,3to support their claim that randomized trials have shown that sinusitis antibiotics for rapid resolution. The word requires is too strong here, since a majority of untreated subjects in both studies were improved or cured at 10 days. Moreover, one was a pediatric study that may not be applicable to adults.2The other was an adult study with methodologic weaknesses.3A primary end point was subjective improvement, but patients and investigators were not blinded to treatment; and the nasal decongestant only group had more bilateral sinusitis and completely opacified sinuses than the lincomycin group, suggesting that more complicated cases might have been assigned to the no-antibiotic group. Interestingly, an authority cited by Williams

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.